WebIt should be noted that dose adjustment is required in patients 65 years or older. Initial prescription - dosage and administration: (see . BNF, SPC) and North of England nce for prescribing LAI for full details) A small test dose should be administered to assess tolerance, then dose and dose interval WebAntipsychotic prescribed above the BNF dose limit (high dose antipsychotic therapy) Underlying cardiac disease (e.g. ischaemic heart disease, congestive heart failure, bradycardia, personal history of long QTc, left ventricular hypertrophy) Family history of long QTc Severe renal or severe hepatic impairment
GUIDELINES FOR THE USE OF HIGH DOSE …
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