Web27 feb. 2024 · Overexpressed gga-miR-16-5p resulted in decreased activity of tumor necrosis factor alpha (TNF-α) and the nuclear factor-kappaB (NF-κB) by qPCR. Furthermore, overexpressed gga-miR-16-5p restricted cell multiplication, cycle progression, and increased apoptosis of MG-infected DF-1 cells, whereas inhibited gga-miR-16-5p led … WebNRF-1 is a transcription factor that regulates the expression of nuclear genes required for mitochondrial respiration (subunits of respiratory complexes) and processing …
American Journal of Respiratory and Critical Care Medicine
WebThe nuclear respiratory factors, NRF-1 and NRF-2, were the first vertebrate nuclear transcription factors implicated in the global expression of multiple mitochondrial … Web25 jun. 2024 · The purpose of this paper was to study the transcriptional regulation of nuclear respiratory factor 1 (NRF1) on nuclear factor kappa B (NF-κB), a key molecule in lipopolysaccharide (LPS)-induced lung epithelial inflammation, and to clarify the mechanism of NRF1-mediated inflammatory response in lung epithelial cells. In vivo, ... royally entertained
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WebA portion of the NRF-1 gene that encodes the nuclear localization signal and the DNA-binding and dimerization domains was replaced through homologous recombination by a β-galactosidase–neomycin cassette. In the mutant allele, β-galactosidase expression is under the control of the NRF-1 promoter. WebNRF-1 is a transcription factor that activates nuclear genes required for respiration as well as genes regulating heme biosynthesis and mitochondrial DNA transcription and replication. NRF-1 has been reported to play an important role in the transcriptional regulation of several genes [30,31,32,33]. WebBackground/aim: The role of nuclear respiratory factor 1 (NRF1) on the prostate cancer progression is controversial. We aimed to investigate the effect of NRF1 overexpression … royally ever after 2