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FPA150 in Patients With Advanced Solid Tumors - Full …
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WebBackground: B7-H4, a B7 immune checkpoint ligand, is expressed at low levels in normal tissue and negatively regulates T-cell function by inhibiting T-cell proliferation and cytokine production. B7-H4 expression is elevated in solid tumors, including breast, ovarian, and endometrial cancers. Targeting B7-H4–expressing tumor cells may relieve B7 … WebAug 24, 2024 · male: h2, h3, h4, h5, c1, c2, c3, c4, c5, b, t1-2 Paralympic road cycling (1–3 September) Jaco van Gass will make his Paralympic debut, competing in the C1-3 road race and on the track. WebOct 1, 2024 · Submitted abstracts Immunotherapy of cancer 1198P FPA150 (B7-H4 antibody) phase I update in advanced solid tumours: Monotherapy and in combination … howden group login